Shirazi was born in the city of Shiraz in October 1236 AD and is known as a very knowledgeable scientist. The full name of the scholar Qotb al-Din al-Shirazi (Qotb al-Din Shirazi) has contributed ideas and fruit of his thoughts in the fields of astronomy, mathematics, medicine, physics, music theory, and Sufism. When he was a child, his father had practiced and taught medicine at Mozaffari Hospital in Shiraz. When he was 14 years old, Shirazi was considered the father to master medical science or medicine.

To deepen his ability in the field of medicine, he then studied with a number of senior doctors such as Kamal al-Din Abu’l Khayr, Sharaf al-Din Bushkani Zaki and Shams Al-Din Mohammad Kishi. The three are doctors who master the legendary book Canon of Medicine by Ibn Sina. After a decade of fulfilling his obligations as a doctor, Shirazi decided to quit. He then began to devote his time to continuing his education under the guidance of a prominent astronomer, Nasir al-Din al-Tusi. He was willing to leave his hometown to be able to learn from Nasir al-Din al-Tusi who built the Maragha observatory.

After reading the comments of Fakhr al-Din Razi at the Canon of Medicine, he was then inspired to comment on the great work of Ibn Sina. While working at the observatory, he also studied astronomy. One of the important scientific projects he completed with al-Tusi was the creation of a new astronomical table in the astronomical book Zij. In his will, al-Tusi advised his son Sila-Din to work with Shirazi in completing the Zij Table.

In the field of mathematics, he produced a phenomenal work entitled Tarjoma-ye Tahrir-e Oqlides. This is a work in the field of geometry written in Persian as outlined in 15 chapters. Most of the books themselves are translations of the work of Nasir al-Din Tusi. This work was completed in November 1282 AD and dedicated to Mo’in Al-Din Solayman Parvana. He also produced Risala fi Harkat al-Daraja, a work in the field of mathematics.

While in the field of astronomy, Shirazi has produced Ektiarat e-Mozafarri. This is a treatise on astronomy in Persia as outlined in four chapters and extracted from his other work, Nehayat El-Edrak. This work itself has been dedicated to Mozaftar-al-Din Bulaq Arsalan. The harakat al-dahraja wa’nesha hayn al-mostawi wa’l-monhani is another work which is a writing as an attachment to Nehayat El-Edrak. In addition, he also wrote the book al-Tuhfat al-Shahiya which he completed in 1284 AD.

Another work in the field of astronomy is the book fa’alta wa la talom fi’l-hay’a, an Arabic-language work in the field of astronomy written for Asil-al-Din, the son of Nasir al-Din Tusi. Other works in the field of astronomy are Sarh Tadkera Nasiriya. In the field of medicine, he produced the book At-Tohfa al-Sa’diya jufa, a complete commentary on the Canon of Avicenna in Arabic. There is also Resala fi’l-Baras, a medical treatise on leprosy in Arabic. At the end of his life, al-Shirazi was very active in teaching the Canon of Medicine and Shefa books written by Ibn Sina to his students in Syria. He then moved to Tabriz. Shirazi died around 1311 AD and was buried in the city of Carandab.